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Skin Test Could Detect Alzheimer's Disease Early
Medical technology is always a good thing, but these researchers are testing (and focusing) on the symptoms of Alzheimer's, rather than the cause of the disease. People will continue to stay dependent on pharmaceutical medicine until this approach to disease is taken seriously. Let’s stop focusing on the detection of disease, and focus on the cause. Maybe this will prevent modern diseases from becoming epidemic. New tests, like the one in this article, are always a step in the right direction, but again, treating the symptoms isn’t going to cure the disease. Let’s use this technology to discover the causes of disease before it has a chance to develop into irreversible “Alzheimer's” symptoms.
To your health!
Dr. Janet Starr Hull
__________________________________________________________________
Skin Test Could Detect Alzheimer's Disease Early
MONDAY, Aug. 14 (HealthDay News) -- A simple skin test that would allow detection of Alzheimer's disease in its earliest stages is working its way to reality.
The work "is based on the hypothesis that Alzheimer's disease doesn't just affect the brain but affects the body systemically," said Dr. Daniel L. Alkon, a lead author of a report on the test published online this week in Proceedings of the National Academy of Sciences.
The test zeroes in on two forms of an enzyme involved in the degradation of amyloid, the protein that accumulates in the brain of someone with Alzheimer's, said Alkon, scientific director of the Blanchette Rockefeller Neurosciences Institute at the West Virginia University Health Sciences Center.
The presence of Alzheimer's disease is indicated by a steep imbalance in the ratio of the two forms of the enzyme, MAP kinase Erk, in skin cells that are exposed to bradykinin, an inflammation-related molecule, Alkon said. That imbalance is not seen in cells of people without dementia or those with other forms of dementia, he said.
The test produced good results when run on 60 tissue samples: 30 from a tissue bank, 30 from autopsy samples of people diagnosed with Alzheimer's disease, Alkon said.
"We have seen a correlation with the duration of the disease," he said. "The earlier it is done in the course of the disease, the larger is the abnormality."
Posted August 2006 | Permanent Link
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